thymus, endometrium, mammary gland, gonads) are active only until a certain age, then they shrink ← such atrophy is called involution in old age, all parenchymatous organs shrink physiologically.aging ( senile atrophy to cachexia or marasmus ) necroses occur with stronger action of the provoking causesġ.they also depend on the intensity and duration of the stimulus.they can be physiological or pathological.sclerosis does not allow regeneration, possible compensatory hypertrophy of the functional parenchyma leads to substantial remodeling.inflammatory atrophy with increased tissue production.this is fat atrophy, which is caused by the disappearance of fat from the cells and the increase of the amorphous component of the intercellular mass ( glycosaminoglycans).similar is the accumulation of lipochrome in atrophic adipose tissue.cell nuclei are pyknotic, cytoplasm more basophilic, storage substances ( glycogen, fat) disappear from the cells.it most often affects tissues with slowly changing cells.the number of cells remains the same, but their size decreases (the opposite of hypertrophy).it arises in skeletal muscles, myocardium, pancreas, salivary glands.the loss of parenchyma cells during numerical atrophy can be masked by the increase of fat tissue in the interstitium (the organ is then normally large or even enlarged, so-called pseudohypertrophy ).if the breakdown of cells occurs rapidly during numerical atrophy, the breakdown products from dying cells cause inflammation with new tissue formation.the result can be the suppression of all lines of hematopoiesis ( aplastic anemia).it is a relative loss of hematopoietic marrow in favor of adipose tissue.an example is numerical bone marrow atrophy ( marrow attenuation).it most often affects tissues with rapid cell turnover.the number of tissue or organ cells decreases (the opposite of hyperplasia).bearing – there is a change in the shape of the organ.diffuse – does not lead to a change in the shape of the organ. 1.3 Secondary changes of atrophic tissueĭistribution of atrophies.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |